This table shows the activity of the 6 main phytocannabinoids on a receptor level. As you can see, there is a lot of room for further cannabinoid research in the future! [R1] [R2]
Phytocannabinoid | CB1 | CB2 | PPARgam | PPARa | 5HT1a | 5HT2a | TRPV1 |
THC | ++ | ++ | +++ | ? | ? | ? | +++ |
CBD | —* | —* | +++ | ? | +++ | ++* | +++ |
CBN | +++ | +++ | ? | ? | ? | ? | ? |
CBG | ++* | ++* | ? | ? | — | ? | +++ |
CBC | +++* | +++* | ? | ? | ? | ? | ? |
Yangonin | ++ | ++* | ? | ? | ? | ? | ? |
(+) = positive allosteric modulator (++) = partial agonist (+++) = full agonist * denotes a weak effect | (-) = negative allosteric modulator (–) = partial antagonist (—) = antagonist ? = unknown or no activity |
For more on the Cannabinoid System, see here…
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